乳臼齒 齒根端 病巢의 免疫學的 觀察
IMMUNOLOGIC ASPECTS OF PERIAPICAL LESIONS IN PRIMARY MOLARST
소속 상세정보
김영숙(金英淑)/Kim Young-Sook
김영진(金永進)/Kim Young Jin
KMID : 0358919860130010043
Abstract
要 約
3才에서 11才사이 兒童의 乳臼齒에 形成된 齒根端 病巢 31 例를 PAP染色方法을 使用하
여 Ig G, Ig A, I gM의 分布를 觀察하여 다음과 같은 結論을 얻었다.
齒根端病巢에서 免疫글로블린의 分布는 I g G가 87.1%, I g A가 54.8%, I g M이 45.1%
의 陽性反應을 나타내었다.
各 病巢의 免疫글로블린의 分布는 炎症程度와 部位에 따라 多樣하였으나 I g G, I g A, I
g M順이었다.
免疫글로블린은 基質化가 養護하고 淋巴球와 形質細胞의 浸潤이 顯著한 誨芽組織에서 多
量存在하였다.
化濃中心部와 中性白血球의 浸潤이 심한 部位는 細胞內 免疫글로블린이 存在하지 않았으
며 渗出性 纖維素網과 周圍細胞間質에 免疫글로블린이 主로 分布하였다.
I g G와 I g A는 島狀의 增殖된 上皮組織直 下部의 洶芽組織內에 多量 分布하였다.
#초록#
This experiment was performed to elucidate the histopathologic distribution of
immunoglobulins, particularly IgG, IgA and IsM in 31 periapical lesions of primary
molars (23:Granuloma, 8: Abscess).
The immunoperoxidase staining method using reagents manufactured by Danish D
AKO company was used in this experiment.
The following results were obtained:
In the 31 periapical lesions, IgG was found in 27 cases (87 1%), IgA in 17 cases
(54.8%) and IgM in 14 cases (45.1%).
The distribution of inlmunoglobulins in periapieal lesions was in great diversity
according to the degree of inflammation and area. But the degree of distribution of
immunoglobulins was Ig G, Ig A IgM in descending order.
More immunoglobulins were found in the granulomatous tissue with moderate or
severe infiltrations of plasma cells and Iymphocytes.
Immunoglobulins were not noted in the liquefied area and severe leukocytes infiltration
area, and massive immunoglbulins were found in exudative fibrin mesh and peripheral
intercell-ular substance.
IgG and IgA was dominant in the well organized granulation tissue around the
proliferating epithelium of island form.
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